![]() ![]() intra-MR icEEG was comparable to that obtained outside the scanner. icEEG–fMRI was well tolerated and no adverse health effect was observed. On scalp EEG–fMRI recordings performed prior to the implantation, no IED were detected. IED were subsequently visually identified on icEEG and their fMRI correlates were mapped using a general linear model (GLM). Simultaneous recordings of fMRI and icEEG were obtained at rest. They were scanned on a 1.5 T MR scanner following a strict safety protocol. Two patients undergoing icEEG with subdural and depth electrodes as part of the presurgical assessment of their pharmaco-resistant epilepsy participated in the study. We performed simultaneous icEEG and functional MRI recordings in epileptic patients to study the haemodynamic correlates of intracranial interictal epileptic discharges (IED). Intracranial EEG (icEEG) has greater sensitivity and spatial specificity than scalp EEG but limited spatial sampling. Simultaneous scalp EEG–fMRI measurements allow the study of epileptic networks and more generally, of the coupling between neuronal activity and haemodynamic changes in the brain.
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